Who is LISA?
This day was super exciting, as the teaching team organized LISA training. LISA is a shortcut for ‘less invasive surfactant administration’.
As many of the new doctors are having their first weeks in the units, Sanya, who is one of the incredible consultants, organized this training. After talking about some theoretical backgrounds everybody had the chance to train this procedure on the dummy- even me ;-)
What is Surfactant?
Surfactant is monomolecular phospholipid layer that extends into bronchioles and small airways of the lung. It also prevents collapse in the smallest airways.
What is LISA?
Preterm infants commonly develop respiratory distress syndrome (RDS) requiring some form of respiratory support and potentially surfactant administration. Treatment with Surfactant, the fluid of wonder, has been shown to reduce risk of death and bronchopulmonary dysplasia in preterm infants. Standard approach involved using a endo-tracheal tube and mechanical ventilation. This ventilation can cause damage to fragile preterm lungs. So, how can we bring this Surfactant into the lungs without intubating? LISAs time to shine. It’s a technique delivering surfactant directly into the lungs via a fine catheter inserted into the trachea.
When is it used?
LISA is perfprmed in infants <32 weeks gestation with fiO2 requirement > 30% at any time in the first 72 hours
Or
in infants ≥ 32 weeks gestation with a persistent fiO2 requirement >40% at any time in the first 72 hours
These guidelines differ between different units.
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